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QSS Skin Brightener (Lightener)  
QSS Skin Brightener (Lightener)

Quintessence® Skin Brightener is a light, easily absorbed cream designed as an alternative to high strength hydroquinone formulations for improving the appearance of facial and hand pigmentation. It can be used for long term face and hand brightening as well as for evening out skin tone. It also possesses excellent moisturizing and antioxidant properties. Quintessence® Skin Brightener is appropriate for all skin types.

PRODUCT ATTRIBUTES:

·        Gradual, uniform lightening

·        Excellent for assisting in the prevention pigmentation problems after Laser, IPL and chemical peel treatments

·        Extremely low cytotoxicity allowing it to be used over extended periods of time (i.e., years)

·        Excellent moisturizer and humectant properties

·        High tyrosinase inhibitor levels

KEY INGREDIENTS:

PHENYLETHYL RESORCINOL): Potent skin lightener and anti-oxidant that is non-irritating with extremely low cytotoxicity. Studies demonstrate it has in vitro anti-oxidant efficacy equivalent to Alpha Tocopherol (Vit. E). Effectiveness Study conducted on 12 Asian subjects (skin type III) showed 0.5% Phenylethyl Resorcinal more effective than 1.0% Kojic Acid.

METHYL DIHYDROXYBENZOATE (Methyl Gentisate):
Effective enzyme inhibitor (1), extremely low cytotoxicity levels with gradual, uniform lightening abilities and may be used over long periods of time without any negative side effects.

Myristoyl Pentapeptide-9: Propietary Lipopeptide that provides anti-wrinkle benefits, while both brightening and helping give the skin a more even tone.

LICORICE EXTRACT (Glycyrrhiza Glabra): Glabridin is the main tyrosinase inhibitor found in licorice. It inhibits tyrosinase activity without affecting DNA synthesis.  Clinical testing proved that glabridin lowered the activities of T1 and T3 tyrosinase isozymes.  Further testing proved that glabridin also possesses anti-inflammatory effects in-vitro (Yolata T., Nishio H., Kubota, et al:) (2).

ARBUTIN:  Naturally found in the leaves of pear trees and certain herbs, Arbutin reverses rather than suppresses tyrosinase activity. It functions as a melanogenesis inhibitor to reduce the appearance of hyperpigmentation and is an effective antioxidant and skin conditioner.

Ingredients/Ingredientes (INCI):   Aqua (water), Butyelne Glycol, Cetearyl Alcohol, Arbutin, Phenylethyl Resorcinol(SymWhite®377), Cyclopentasiloxane, Cyclohexasiloxane, Dimethicone, Methyl Dihydroxybenzoate (Methyl Gentisate), Coco-Caprylate/Caprate, Behenoxy Dimethicone, Behenyl Alcohol, Glyceryl Stearate, PEG-100 Stearate, Cetearyl Glucoside, Behenyl Methosulfate, Morus Alba (Leaf) Extract, Glycyrrhiza Glabra (Licorice) Extract, Arctostaphylos Uva Ursi (Leaf) Extract, Scutellaria Extract, Betaglucan, Magnesium Ascorbyl Phosphate, Phenoxyethanol, Sodium Carboxymethyl Betaglucan, Tocopheryl Acetate, Palmitoyl Hydrolyzed Wheat Protein, Myristoyl Pentapeptide-9, Caprylyl Glycine.

Directions for use:  After cleansing with Quintessence Purifying Cleanser, apply Quintessence Skin Brightener to problem areas for one month prior to full face/hand application. After problems areas have lightened to desired color, Quintessence Skin Brightener may be applied to entire area to achieve an even color.

Caution: Prior to application of Quintessence Skin Brightener on a regular basis, perform a sensitivity test by applying it to a small area of your forearm.  If extreme redness or itching occurs, discontinue use immediately.

REFERENCES

1.       Curto EV, Kwong C, Hermersdorfer H, Glatt H, Santis C, Virador V, Hearing VJ Jr, Dooley TP, Inhibitors of mammalian melanocyte tyrosinase: in vito comparisons of alkyl esters of gentisic acid with other putative inhibitors: Biochem Pharmacol, 1999, Mar. 15; 57(6):663-672

2.       Yokoto T, Nishio H, Kubota Y et el: The inhibitory effect of glabridrin from licorice extract on melanogenisis and inflamation. Pigment Cell Res 11:355, 1998

3.       Baumann, Leslie: Cosmetic Dermatology Principles & Practice, McGraw-Hill 2002;  99-102

4.       Nakagama M, Kawai K, Kawai K: Contact Allergy to Kojic Acid in Skin Care Products. Contact Dermatitis 32:9, 1995

5.       Kameyama K, Sakai C, Kondoh S, et al: Inhibitory effect of magnesium L-ascorbyl -2-phosphate (WV-PMG) on melanogenisis in vitro and in vivo. J Am Acad Dermatol 34:29 1996

6.       Kasrae B: Peroxidase-Mediated Mechanisms and Depigmenting Agents; Dermatology 2002;205:329–339

 

 

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